Details for gene set NCI_TRAIL SIGNALING PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	set01_ATM_minus_versus_SCID
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	NCI_TRAIL SIGNALING PATHWAY
Enrichment Score (ES)	-0.313202
Normalized Enrichment Score (NES)	-1.5990154
Nominal p-value	0.0
FDR q-value	0.37429228
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	YWHAZ	8	16.194	0.0210	No
2	RAP1A	50	10.899	0.0334	No
3	UBE2D3	95	9.312	0.0437	No
4	FCGR2B	169	8.256	0.0512	No
5	KRAS	179	8.095	0.0615	No
6	CYCS	295	6.886	0.0652	No
7	BLK	301	6.807	0.0740	No
8	MAPK8	369	6.349	0.0792	No
9	KPNB1	470	5.778	0.0822	No
10	XPO1	482	5.700	0.0892	No
11	PTPRC	487	5.647	0.0965	No
12	CHUK	537	5.425	0.1014	No
13	IGF1	591	5.167	0.1058	No
14	YWHAG	608	5.096	0.1117	No
15	GAS2	624	5.024	0.1177	No
16	MAP3K7	785	4.594	0.1163	No
17	APP	805	4.540	0.1214	No
18	TRAF6	821	4.500	0.1267	No
19	PIK3R1	880	4.360	0.1297	No
20	YWHAQ	965	4.155	0.1313	No
21	KPNA1	973	4.137	0.1365	No
22	BCL3	989	4.105	0.1412	No
23	HSP90AA1	1006	4.060	0.1458	No
24	RAC1	1090	3.907	0.1471	No
25	DAP3	1259	3.622	0.1441	No
26	EIF4G1	1269	3.611	0.1485	No
27	ASAH1	1298	3.560	0.1519	No
28	CDKN2A	1314	3.535	0.1559	No
29	EGR1	1388	3.442	0.1570	No
30	GSK3B	1406	3.424	0.1608	No
31	PTPRK	1418	3.413	0.1647	No
32	POU2F1	1447	3.374	0.1679	No
33	TOP1	1486	3.326	0.1705	No
34	BID	1540	3.273	0.1724	No
35	CYLD	1552	3.260	0.1762	No
36	PRKCA	1554	3.257	0.1804	No
37	CFL2	1577	3.229	0.1837	No
38	PLCG2	1658	3.146	0.1841	No
39	YWHAB	1690	3.120	0.1868	No
40	MAP2K4	1720	3.094	0.1895	No
41	ARFIP2	1744	3.073	0.1925	No
42	MAPK9	1747	3.072	0.1965	No
43	IL5	1777	3.048	0.1992	No
44	PDE3B	1787	3.039	0.2028	No
45	IKBKB	1816	3.007	0.2054	No
46	LMNA	1865	2.968	0.2071	No
47	RHEB	1909	2.934	0.2090	No
48	CD22	2037	2.822	0.2069	No
49	IL2RA	2077	2.788	0.2087	No
50	EGR2	2110	2.763	0.2109	No
51	PPP3CB	2125	2.754	0.2139	No
52	GATA3	2129	2.751	0.2174	No
53	RAN	2245	2.675	0.2156	No
54	NFKB1	2265	2.665	0.2182	No
55	MAPK1	2313	2.637	0.2195	No
56	NFKBIB	2348	2.618	0.2214	No
57	CD79A	2423	2.578	0.2214	No
58	ARRB2	2541	2.515	0.2193	No
59	EGR4	2573	2.496	0.2212	No
60	IBTK	2735	2.420	0.2169	No
61	GRB2	3033	2.283	0.2062	No
62	TIAM1	3094	2.261	0.2065	No
63	PPARG	3135	2.246	0.2076	No
64	NR4A1	3314	2.175	0.2022	No
65	RASA1	3405	2.139	0.2009	No
66	PPP3CC	3440	2.129	0.2021	No
67	EP300	3501	2.101	0.2021	No
68	TNFRSF10B	3601	2.063	0.2003	No
69	VIM	3632	2.050	0.2016	No
70	RHOA	3636	2.049	0.2042	No
71	BAX	3661	2.040	0.2057	No
72	NFATC2	3788	1.997	0.2026	No
73	PLD2	3840	1.978	0.2028	No
74	PRKCQ	3914	1.954	0.2020	No
75	HCK	3997	1.930	0.2008	No
76	AKT1	4013	1.922	0.2026	No
77	DFFB	4105	1.893	0.2009	No
78	TNFSF10	4300	1.829	0.1944	No
79	IRF4	4324	1.821	0.1957	No
80	CDK4	4473	1.777	0.1912	No
81	MYC	4818	1.663	0.1775	No
82	PLEKHA1	5092	1.575	0.1670	No
83	POU2F2	5136	1.563	0.1671	No
84	JUN	5219	1.538	0.1653	No
85	CD19	5267	1.525	0.1652	No
86	E2F1	5666	1.419	0.1487	No
87	RELB	5844	1.372	0.1423	No
88	BTK	5881	1.361	0.1425	No
89	PRF1	6136	1.301	0.1325	No
90	PRKCZ	6358	1.249	0.1239	No
91	MKNK1	6427	1.234	0.1224	No
92	PTPN6	6588	1.199	0.1166	No
93	CDKN1A	6632	1.188	0.1162	No
94	GSN	6663	1.179	0.1163	No
95	PDGFA	6734	1.163	0.1146	No
96	PIM1	6823	1.141	0.1121	No
97	CAMK2G	6891	1.124	0.1105	No
98	CASP3	7041	1.089	0.1050	No
99	PAWR	7235	1.043	0.0975	No
100	TNF	7390	1.007	0.0917	No
101	ZAP70	7530	0.981	0.0866	No
102	NFATC3	7606	0.960	0.0844	No
103	YES1	7730	0.934	0.0800	No
104	APAF1	7858	0.905	0.0753	No
105	SOS1	7915	0.892	0.0739	No
106	LRDD	8142	0.837	0.0646	No
107	INSR	8289	0.805	0.0589	No
108	SRC	8316	0.801	0.0587	No
109	FOS	8574	0.740	0.0479	No
110	FOXP3	8577	0.740	0.0487	No
111	FOSL1	8671	0.720	0.0454	No
112	CASP1	8748	0.700	0.0428	No
113	SFN	8858	0.672	0.0387	No
114	PTGS2	9200	0.592	0.0237	No
115	AKT1S1	9328	0.564	0.0186	No
116	IFNG	9533	0.513	0.0099	No
117	RNF128	9692	0.466	0.0032	No
118	DOK1	9793	0.440	-0.0008	No
119	BLNK	9834	0.428	-0.0021	No
120	MAP3K8	10208	0.325	-0.0189	No
121	DGKA	10432	0.260	-0.0289	No
122	PPP2R5D	11123	0.055	-0.0606	No
123	BIRC2	11518	-0.071	-0.0787	No
124	CTLA4	11581	-0.092	-0.0814	No
125	CD40LG	11902	-0.186	-0.0960	No
126	CASP4	11934	-0.193	-0.0971	No
127	PRKDC	12100	-0.245	-0.1044	No
128	INPPL1	12157	-0.262	-0.1067	No
129	CALM2	12170	-0.266	-0.1069	No
130	AKAP5	12259	-0.290	-0.1106	No
131	EIF4EBP1	12380	-0.326	-0.1157	No
132	MAP2K1	12682	-0.417	-0.1290	No
133	IL3	12907	-0.478	-0.1387	No
134	GZMB	12914	-0.481	-0.1384	No
135	CD79B	12935	-0.487	-0.1386	No
136	CD72	12944	-0.489	-0.1384	No
137	GSK3A	12974	-0.496	-0.1390	No
138	BIRC3	13103	-0.532	-0.1442	No
139	CASP8	13264	-0.577	-0.1509	No
140	FASLG	13618	-0.676	-0.1663	No
141	SMPD1	13655	-0.684	-0.1670	No
142	RPS6	13992	-0.776	-0.1815	No
143	YWHAH	14065	-0.795	-0.1838	No
144	BAD	14127	-0.811	-0.1855	No
145	EGR3	14289	-0.850	-0.1918	No
146	MAP3K14	14291	-0.850	-0.1908	No
147	FKBP1A	14387	-0.874	-0.1940	No
148	NFKBIA	14429	-0.885	-0.1947	No
149	LMNB2	14472	-0.899	-0.1955	No
150	ETS1	14561	-0.921	-0.1983	No
151	LMNB1	14609	-0.933	-0.1993	No
152	EIF4A1	14880	-1.009	-0.2104	No
153	SYK	15080	-1.067	-0.2182	No
154	SH3BP5	15224	-1.108	-0.2233	No
155	RIPK1	15476	-1.175	-0.2333	No
156	TNFAIP3	15596	-1.207	-0.2372	No
157	PRKCH	15876	-1.279	-0.2484	No
158	ARF1	15903	-1.285	-0.2479	No
159	MAF	16023	-1.316	-0.2517	No
160	AP2A1	16318	-1.395	-0.2634	No
161	LIMK1	16391	-1.413	-0.2649	No
162	REL	16499	-1.441	-0.2679	No
163	ERC1	16624	-1.475	-0.2717	No
164	SMPD3	16794	-1.523	-0.2775	No
165	EGF	16992	-1.583	-0.2845	No
166	CALM1	17015	-1.591	-0.2834	No
167	FGR	17077	-1.610	-0.2841	No
168	HRAS	17104	-1.619	-0.2832	No
169	SLC3A2	17131	-1.624	-0.2822	No
170	SHC1	17343	-1.699	-0.2897	No
171	CTSD	17466	-1.742	-0.2931	No
172	ELK1	17468	-1.742	-0.2908	No
173	GOSR2	17590	-1.781	-0.2940	No
174	IRS1	17725	-1.828	-0.2978	No
175	PAG1	17852	-1.870	-0.3012	No
176	AKT3	17896	-1.889	-0.3007	No
177	TBC1D4	17924	-1.896	-0.2994	No
178	COPA	18077	-1.950	-0.3038	No
179	MAP3K1	18221	-2.003	-0.3078	No
180	CSF2	18330	-2.052	-0.3101	No
181	PDPK1	18359	-2.062	-0.3087	No
182	BAG4	18401	-2.080	-0.3078	No
183	VAV2	18451	-2.098	-0.3073	No
184	JUNB	18468	-2.107	-0.3053	No
185	MDM2	18548	-2.138	-0.3061	No
186	ACTA1	18569	-2.146	-0.3042	No
187	DIABLO	18642	-2.180	-0.3046	No
188	IL4	18791	-2.244	-0.3085	No
189	MAPK3	18809	-2.253	-0.3063	No
190	BCL10	18959	-2.318	-0.3101	Yes
191	PPP3CA	18969	-2.322	-0.3075	Yes
192	RELA	19001	-2.341	-0.3058	Yes
193	ARHGDIB	19075	-2.378	-0.3061	Yes
194	CLTB	19090	-2.384	-0.3036	Yes
195	PRKRA	19098	-2.389	-0.3008	Yes
196	SREBF1	19131	-2.408	-0.2991	Yes
197	FADD	19136	-2.411	-0.2961	Yes
198	PLEKHA2	19149	-2.417	-0.2934	Yes
199	PRKCD	19153	-2.418	-0.2904	Yes
200	CREBBP	19159	-2.422	-0.2874	Yes
201	PTPN1	19166	-2.425	-0.2845	Yes
202	NRAS	19179	-2.433	-0.2819	Yes
203	PRKACA	19225	-2.460	-0.2807	Yes
204	PLCG1	19227	-2.460	-0.2775	Yes
205	RIPK2	19231	-2.465	-0.2744	Yes
206	NFKB2	19250	-2.474	-0.2720	Yes
207	PARP1	19253	-2.476	-0.2688	Yes
208	SLC2A4	19344	-2.517	-0.2696	Yes
209	CDKN1B	19399	-2.549	-0.2688	Yes
210	MAPK14	19612	-2.666	-0.2750	Yes
211	CRADD	19613	-2.666	-0.2715	Yes
212	ARHGEF6	19656	-2.685	-0.2699	Yes
213	PRKAB1	19660	-2.688	-0.2665	Yes
214	IKBKG	19692	-2.704	-0.2644	Yes
215	MAP2K2	19707	-2.715	-0.2614	Yes
216	FRAP1	19809	-2.769	-0.2624	Yes
217	KSR1	19844	-2.795	-0.2603	Yes
218	MALT1	20136	-2.989	-0.2698	Yes
219	AKT2	20142	-2.992	-0.2661	Yes
220	NUMA1	20161	-3.004	-0.2630	Yes
221	CASP2	20246	-3.056	-0.2628	Yes
222	CSNK2A1	20266	-3.069	-0.2597	Yes
223	SPHK2	20286	-3.088	-0.2565	Yes
224	CARD11	20320	-3.115	-0.2539	Yes
225	CASP9	20330	-3.121	-0.2502	Yes
226	PTK2	20343	-3.132	-0.2466	Yes
227	TSC2	20379	-3.156	-0.2441	Yes
228	RPS6KB1	20405	-3.174	-0.2410	Yes
229	PIK3CA	20435	-3.207	-0.2382	Yes
230	MAPKAP1	20441	-3.214	-0.2341	Yes
231	PTEN	20449	-3.224	-0.2302	Yes
232	ARHGEF7	20465	-3.239	-0.2266	Yes
233	EIF4E	20471	-3.243	-0.2226	Yes
234	VAV1	20481	-3.253	-0.2187	Yes
235	CSNK1A1	20494	-3.270	-0.2150	Yes
236	NUP214	20503	-3.276	-0.2110	Yes
237	FYN	20519	-3.289	-0.2074	Yes
238	CAMK4	20719	-3.468	-0.2120	Yes
239	RAF1	20726	-3.476	-0.2077	Yes
240	PPP5C	20735	-3.488	-0.2035	Yes
241	CBLB	20738	-3.491	-0.1990	Yes
242	CALM3	20830	-3.605	-0.1984	Yes
243	DAPP1	20841	-3.613	-0.1941	Yes
244	SATB1	20856	-3.642	-0.1899	Yes
245	DFFA	20981	-3.791	-0.1907	Yes
246	CD4	20985	-3.795	-0.1858	Yes
247	ARF5	21069	-3.919	-0.1845	Yes
248	FBXW11	21133	-4.021	-0.1821	Yes
249	EEF2	21183	-4.108	-0.1789	Yes
250	ARF6	21229	-4.197	-0.1755	Yes
251	ARFGAP1	21233	-4.207	-0.1701	Yes
252	AP2M1	21262	-4.285	-0.1657	Yes
253	CASP6	21299	-4.360	-0.1616	Yes
254	TRAF2	21367	-4.531	-0.1587	Yes
255	FKBP8	21447	-4.734	-0.1562	Yes
256	BCL2	21470	-4.794	-0.1509	Yes
257	GGA3	21488	-4.832	-0.1453	Yes
258	ITK	21521	-4.965	-0.1402	Yes
259	ITCH	21548	-5.062	-0.1347	Yes
260	CFLAR	21557	-5.089	-0.1284	Yes
261	CSK	21565	-5.125	-0.1220	Yes
262	TRADD	21592	-5.207	-0.1163	Yes
263	YWHAE	21593	-5.209	-0.1094	Yes
264	TNFRSF1A	21616	-5.292	-0.1035	Yes
265	TBX21	21663	-5.487	-0.0984	Yes
266	TP53	21670	-5.532	-0.0914	Yes
267	TSC1	21728	-5.921	-0.0862	Yes
268	GBF1	21781	-6.360	-0.0802	Yes
269	LCK	21782	-6.376	-0.0718	Yes
270	NFATC1	21808	-6.771	-0.0640	Yes
271	CLTA	21812	-6.848	-0.0551	Yes
272	MAP4K4	21855	-7.660	-0.0470	Yes
273	PRKCE	21859	-7.723	-0.0369	Yes
274	MEF2D	21866	-7.893	-0.0268	Yes
275	ATM	21922	-11.494	-0.0142	Yes
276	CASP7	21924	-11.616	0.0011	Yes